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May 15, 2009Cell CycleOpen Access

Role of p53 in the anti-proliferative effects of Sirt1 inhibition in prostate cancer cells

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Authors

BJBrittney Jung‐HynesUW Health University HospitalNANihal AhmadUniversity of Wisconsin System

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Jung‐Hynes et al. (2009) studied this question.

synapsesocial.com/papers/6ab08ac6c67f207ce795940ehttps://doi.org/10.4161/cc.8.10.8408
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Control of Multidrug Resistance Gene <i>mdr1</i> and Cancer Resistance to Chemotherapy by the Longevity Gene <i>sirt1</i>2005 · 166 citations
  2. 2Cancer-Specific Functions of SIRT1 Enable Human Epithelial Cancer Cell Growth and Survival2005 · 296 citations
  3. 3Sirtuin 1 Is Required for Antagonist-Induced Transcriptional Repression of Androgen-Responsive Genes by the Androgen Receptor2007 · 95 citations