This perspective article addressed a rising question if optimizing meal timing can help minimize obesity and diabetes (diabesity) via optimizing glucose and insulin circadian metabolism. Meal properties including timing, sequence, and frequency are of metabolic importance in ruminants and humans. The modern man consumes fast foods at wrong times of the 24-h circadian period. Suboptimal meal timing and inadequate physical activity can impair normal biological rhythmicity of glucose and insulin metabolism, which may lead to diabetes. Type 2 diabetes mellitus (T2D) and obesity could, thus, largely be a consequence of suboptimal meal timing and lifestyle. Avoiding sugar- and carbohydrate-rich evening and nocturnal meals should help improve glucose and insulin metabolism. Optimal meal timing is a growing practice that should be incorporated into healthy nutritional programs to help avert obesity and T2D in today’s stressful life. Subsequently, nutrient-dense evening and night meals must be avoided to reduce diabesity risk.
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Nikkhah et al. (2022) studied this question.
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