Acromegaly and Gastrointestinal Adenocarcinomas

Letters and Corrections15 September 1988Acromegaly and Gastrointestinal AdenocarcinomasFrederick H. Ziel, MD, Anne L. Peters, MDFrederick H. Ziel, MDSearch for more papers by this author, Anne L. Peters, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-109-6-514_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor:The long-term management of acromegalic patients should include screening for colonic polyps and colon carcinoma as reported by Klein and colleagues (1) and Ituarte and colleagues (2). This screening is especially important, as patients usually have many years of exposure to excess growth hormone and insulin-like growth factor 1, either because their diagnosis is often delayed or their response to conventional treatments is slow or incomplete (3). This prolonged exposure to excess growth factors may promote tumorigenesis (1). In the past year, the three patients with acromegaly who were treated at our endocrine clinic were found to...References1. KleinParveenGavalerVanthiel IGJD. Colonic polyps in patients with acromegaly. Ann Intern Med. 1982;97:27-30. LinkGoogle Scholar2. ItuartePetnniHershman EJJ. Acromegaly and colon cancer. Ann Intern Med. 1984;101:627-8. LinkGoogle Scholar3. Reichlin S. Acromegaly. Medical Grand Rounds. 1982;1:9-24. Google Scholar4. MelmedZielDownsBraunsteinFrohman SFTGL. Medical management of acromegaly due to ectopic production of growth hormone releasing hormone by a carcinoid tumor. J Clin Endocrinol Metab. 1988: [In press]. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cedars-Sinai Medical Center UCLA School of Medicine Los Angeles, CA 90048 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIs Diabetes a Risk Factor for Colorectal Cancer?Acromegaly, growth hormone and cancer riskCancers Associated with AcromegalyRisk of Colorectal Neoplasm in Patients with Acromegaly and its Relationship with Serum Growth Hormone LevelsAcromegaly and CancerInsulin, Insulin-Like Growth Factors and Colon Cancer: A Review of the EvidenceInsulin-Like Growth Factor I and the Development of Colorectal Neoplasia in Acromegaly*Vegan proteins may reduce risk of cancer, obesity, and cardiovascular disease by promoting increased glucagon activityCancer in AcromegalyNutrition, hormones, and breast cancer: Is insulin the missing link?Insulin and colon cancerAcromegaly and gastrointestinal cancer 15 September 1988Volume 109, Issue 6Page: 514-515KeywordsAcromegalyAdenocarcinomaColonGrowth factorsGrowth hormoneInsulin like growth factor 1 Issue Published: 15 September 1988 PDF downloadLoading ...