Key result
Genomic sequencing links the 2024 acute hemorrhagic conjunctivitis outbreak to a recombinant coxsackievirus A24 strain.
Why the study?
An outbreak of acute hemorrhagic conjunctivitis in Mayotte and Madagascar in early 2024 was caused by a different lineage of coxsackievirus A24 variant, with a putative recombinant strain characterized by full-length genome sequencing.
Observational
Yes
The 2024 outbreak of acute hemorrhagic conjunctivitis in the South West Indian Ocean was caused by a distinct, putative recombinant lineage of coxsackievirus A24 variant.
Answers are grounded in this paper and cite their sources.
Identifies recombinant coxsackievirus A24 variant in 2024 outbreaks; leaves open effects on transmissibility and need for enhanced surveillance.
In early 2024, an outbreak of acute hemorrhagic conjunctivitis occurred in Mayotte and in Madagascar, two islands in the Indian Ocean. Real-time diagnosis and genotyping identified a different lineage of coxsackievirus A24 variant (CVA24v) from the current Asian outbreak. Although no recombination event had been detected in all previously reported CVA24v-associated outbreaks associated with the subgenotype IV, we characterized a putative recombinant strain by full-length genome sequencing.
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Mirand et al. (2025) conducted an observational in Acute hemorrhagic conjunctivitis. Coxsackievirus A24 variant (CVA24v) infection was evaluated on Identification and genomic characterization of the outbreak strain. Genomic sequencing of the 2024 acute hemorrhagic conjunctivitis outbreak in Mayotte and Madagascar identified a putative recombinant strain of the coxsackievirus A24 variant.
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