Is ipsilateral administration of COVID-19 vaccine boosters the optimal approach?

This is the authors' abstract. We don't add key points for this paper.

We recently examined the effects of ipsilateral versus contralateral administration of a double-dose homologous mRNA-based vaccination regimen in a SARS-CoV-2 naive population.1 In their correspondence, Iro and Buckland acknowledge that ipsilateral vaccination was associated with a more favourable immune response, and have made a valuable contribution to extend our discussion regarding the underlying mechanisms and relevance of our findings for further COVID-19 immunization events and other vaccines.