Respirable cellulose fibres were less toxic in vitro than the mineral fibres crocidolite and MMVF10. Short-term inhalation of cellulose caused an inflammatory lung response which resolved despite continuing exposure. Intraperitoneal injection of cellulose fibres induced sarcomas rather than mesotheliomas at the highest dose (10 9 WHO fibres), while the two middle doses (10 7 and 10 8 fibres) each produced a mesothelioma. Further work is required to examine the pulmonary effects of respirable cellulose fibres.
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Cullen et al. (2002) studied this question.
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