Key result
WSES Sepsis Severity Score reliably predicts in-hospital mortality in complicated intra-abdominal infections with ~0.83 AUROC.
Why the study?
The ability of the World Society of Emergency Surgery Sepsis Severity Score to prognosticate fatal outcomes in patients with complicated intra-abdominal infections in a local Bulgarian setting was evaluated.
Does the WSES SSS accurately predict in-hospital mortality in adult patients with complicated intra-abdominal infections requiring emergency surgery?
Observational (n=110)
No
Does the WSES SSS accurately predict in-hospital mortality in adult patients with complicated intra-abdominal infections requiring emergency surgery?
The WSES SSS is a reliable predictor of in-hospital mortality in patients with complicated intra-abdominal infections requiring emergency surgery.
Answers are grounded in this paper and cite their sources.
May aid risk stratification in emergency surgery for complicated intra-abdominal infections; leaves open prospective validation before routine use.
PURPOSE: To evaluate the ability of World Society of Emergency Surgery Sepsis Severity Score (WSES SSS) to prognosticate the fatal outcome in our local setting and compare the findings with global data. METHODS: The retrospective study involved 110 patients with complicated intra-abdominal infections (cIAIs) admitted to Department of Surgical Diseases at a University hospital. All adult patients who required emergency surgery due to cIAIs from January 2017 to July 2019 were included. We assessed the prognostic performance of WSES SSS using area under receiver operating characteristics (AUROC) curves and analyzed the coordinates of the curves. RESULTS: The observed in-hospital mortality was 22.7%. WSES SSS was significantly higher in non-survivors compared to survivors - 7(5-8) points vs. 3(0-5) points, p < 0.0001. The established AUROC value of WSES SSS for outcome prediction was 0.825 (0.749-0.902). We have identified sensitivity of 92% and specificity of 68.2% for cut-off value > 4 points. CONCLUSION: The WSES SSS was shown as a practical and reliable mortality predictor in Bulgarian patients with cIAIs.
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Dimitrov et al. (2021) conducted an observational in Complicated intra-abdominal infections (n=110). WSES Sepsis Severity Score was evaluated on In-hospital mortality prediction (AUROC) (AUROC 0.825, 95% CI 0.749-0.902, p=<0.0001). The WSES Sepsis Severity Score reliably predicted in-hospital mortality in patients with complicated intra-abdominal infections, yielding an AUROC of 0.825.
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