An insulin-stimulating protein was isolated from soybean seed.This protein was the major component of a fraction which was adsorbed on cholic acid-conjugated Sepharose 4B, and is suggested to interact with bile salt anions in a specific fashion.The protein had no insulin-like activityper se, but it enhanced the in vitro inhibitory action of insulin on fat decomposition that was accelerated by epinephrine in rat adipose cells.
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MAKING et al. (1988) studied this question.