Freezing of oocytes as fertility preservation for benign medical and social indication

Cryopreservation of oocytes as a way of preserving fertility for future use can be considered for certain benign diseases and conditions. Benign ovarian cysts, BRCA 1/2 mutation carriers, genetic conditions such as Turner syndrome and Fragile X mutation carriers, and even a low ovarian reserve of unknown origin are examples of such conditions. However, the evidence of the advantage of the procedure is sparse in terms of live births. In general, the recommendation is to freeze oocytes before the age of 38 and preferably >15-20 oocytes.