Advanced in the Synthesis of Kaurane Diterpenoids

This is the authors' abstract. We don't add key points for this paper.

Kaurane, especially ent-kaurane diterpenoids are integral parts of terpenoid natural products, and possess various bioactivities, including antibacterial, antitumor, antimalarial and antiviral activities.Additionally, as a result of intramolecular oxidations, cleavages and rearrangements, the tetracyclic ent-kaurane also shows attractive structural diversity.Hence, the total syntheses of ent-kauranes have evoked a great deal of interest in the synthetic community.This review presents the recent advances in the synthesis of ent-kaurane and kauranediterpenoids.Keywords diterpenoids;