Peroperative venography to ensure accurate sapheno-popliteal vein ligation.

Bone marrow showing lysed nuclear material lying among normal cells.other medication was cimetidine, which she took throughout her stay in hospital.Her total white cell count remained between 0-8 and 1-5 x 109/1 for six days with 0-10 % neutrophils.The total white cell count increased on the seventh day and two weeks after admission was 17-8 x 109/1 with 76 % neutrophils.A skin biopsy showed changes consistent with the diagnosis of scleroderma.Intravenous pyelography, cystoscopy, and retrograde pyelography showed nothing abnormal.Renal arteriography showed reduced cortical blood flow with irregularity and beading of the interlobular, arcuate, and interlobar arteries.A renal biopsy showed changes consistent with malignant scleroderma.The patient remained anuric and was transferred to another renal unit for chronic haemodialysis but died soon after.