Synthesis of copper(i) chelates based on heterocyclic thioamides

The paper presents modern data on the complexation of CuHal halides (Hal = Cl, Br, I; duration - 5 hours; temperature – 60-70°C) with arylamides of benzimidazole-2-thiocarboxylic acid HLI-X in alkaline aqueous-methanol solution. Such interaction forms CuLI-X chelates with a yield of 96–99% (method A), while the interaction of Cu2O (duration - 8 hours; temperature – 70-75°C) with thioamides HLI-X in methanol forms CuLI-X chelates with a yield of 90–95% (method B). The composition and structure of the new synthesized copper(I) chelates were studied by elemental analysis and IR spectroscopy. The use of copper(I) chelates as synthons in the production of biologically active compounds and new materials for technology is proposed.