Answers are grounded in this paper and cite their sources.
Buprenorphine was introduced as a potent analgesic with low abuse potential. Reports of buprenorphine abuse by opiate abusers have accumulated over the years, highlighting its use as a cheap alternative to heroin. The lower potency compared with heroin is being compensated by using a cocktail of buprenorphine with benzodiazepines or cyclizine. This study of 18 cases seen over 3 years broadly confirms these findings. Four cases reported haematemesis during acute withdrawal, a symptom not reported in earlier studies.
No takes yet. Share an insight, caveat, or question.
Singh et al. (1992) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: