Key result
Metabolic syndrome is strongly linked to co-occurring CAD and PVD.
Why the study?
Metabolic syndrome is strongly associated with coronary artery disease and peripheral vascular disease, with a marked interrelationship between these cardiovascular diseases requiring clinical awareness and evaluation.
Clinicians should be aware of the strong association between metabolic syndrome, coronary artery disease, and peripheral vascular disease to institute risk reduction measures.
Answers are grounded in this paper and cite their sources.
May prompt dual vascular screening in metabolic syndrome; leaves open prospective trials to guide interventions.
Metabolic syndrome has a very strong association with both forms of cardiovascular (CV) disease - coronary artery disease and peripheral vascular disease. There is also a marked interrelationship between the two forms of CV disease. When one form of CV disease is present, the other should be strongly suspected and the possible occurrence of associated vascular events should be clinically evaluated. When three of the five major components that define metabolic syndrome are present, the clinical evidence indicates that one or both forms of CV disease are present, at least in incipient form. To give maximum clinical benefit to the patient at risk, the clinician must be aware of these associations, look for them and institute the measures that can reduce the risk of progression.
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Thomas F. Whayne (2010) conducted a review in Metabolic syndrome, peripheral vascular disease, and coronary artery disease. Metabolic syndrome was evaluated. Metabolic syndrome is strongly associated with both coronary artery disease and peripheral vascular disease, which frequently co-occur and require clinical evaluation and risk reduction measures.
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