Key result
Gastric bypass linked to a ~68% improvement in HRQoL for obese women at one year.
Why the study?
Improving health-related quality of life along with decreasing obesity-related morbidity is a key goal of bariatric surgery, but the relationship between weight loss and HRQoL after gastric bypass is unclear.
Does gastric bypass improve health-related quality of life in obese women at 1 year?
Cohort (n=139)
Does gastric bypass improve health-related quality of life in obese women at 1 year?
Gastric bypass significantly improves health-related quality of life in obese women at 1 year, driven by the achieved BMI rather than the absolute amount of weight loss.
Gastric bypass may enhance short-term HRQoL in obese women; leaves open durability and generalizability.
BACKGROUND/AIMS: Improving health-related quality of life (HRQoL) along with decreasing obesity-related morbidity is one of the cornerstones of bariatric surgery. The aim of the study was to investigate how losing weight influences the HRQoL 1 year after gastric bypass and whether HRQoL prior to surgery predicts the amount of weight loss 1 year after gastric bypass. METHODS: One hundred and thirty-nine obese women [median (range): age 45 years (20-71), BMI 44 (29-88)] admitted for gastric bypass were selected prospectively and completed the Nottingham Health Profile (NHP) quality of life questionnaire before and 1 year after surgery. RESULTS: Weight loss 1 year after gastric bypass was significant [-37 kg (9-74), p < 0.001] and led to an improvement of quality of life [NHP total score before surgery 62 (39-76) and after surgery 20 (7-65), p < 0.001]. CONCLUSIONS: HRQoL improves dramatically 1 year after gastric bypass. This HRQoL improvement is not influenced by the amount of weight loss, but rather by the BMI achieved at that time.
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Klingemann et al. (2009) conducted a cohort in Obesity (n=139). Gastric bypass vs. Before surgery (baseline) was evaluated on Health-related quality of life (Nottingham Health Profile total score) (p=<0.001). Gastric bypass significantly improved health-related quality of life in obese women at 1 year, with median NHP total scores decreasing from 62 to 20 (p<0.001).
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