Key result
Surgical or hybrid treatment of acute type A dissection complicated by mesenteric malperfusion was associated with 42% hospital mortality, versus 72% for endovascular and 95% for medical therapy.
Why the study?
Does hybrid repair improve hospital mortality in patients with acute type A aortic dissection and visceral malperfusion syndrome compared to medical or endovascular therapy alone?
Does hybrid repair improve hospital mortality in patients with acute type A aortic dissection and visceral malperfusion syndrome compared to medical or endovascular therapy alone?
Absolute Event Rate: 42% vs 95%
Surgical/hybrid treatment of acute type A aortic dissection complicated by mesenteric malperfusion syndrome is associated with lower hospital mortality compared to medical or endovascular therapy alone.
Mesenteric malperfusion syndrome (MMP) caused by acute type A dissection (AAD) is a rare, often clinically silent and fatal complication.1 In the prospective, multicentric German Registry for Acute Aortic Dissection Type A and the International Registry for Acute Dissection (IRAD), mesenteric malperfusion was present in 5.8% (2137 patients) and 3.8% (1809 patients), respectively.2,3 As reported from the IRAD registry, hospital mortality was 95% with medical (conservative) therapy, 72% after endovascular, and 42% after surgical/hybrid treatment of AAD complicated by MMP and ultimately linked to a 3- to 4-fold greater mortality compared with patients without malperfusion.
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Liakopoulos et al. (2021) conducted an editorial in Acute type A aortic dissection with mesenteric malperfusion syndrome. Surgical/hybrid treatment vs. Medical (conservative) therapy was evaluated on Hospital mortality. Surgical or hybrid treatment of acute type A dissection complicated by mesenteric malperfusion was associated with 42% hospital mortality, versus 72% for endovascular and 95% for medical therapy.
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