Chloroquine in the Treatment of Infectious Mononucleosis

Article1 December 1962Chloroquine in the Treatment of Infectious MononucleosisRAY G. COWLEY, JOHN E. MYERS JR.RAY G. COWLEY, JOHN E. MYERS JR.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-6-937 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptInfectious mononucleosis is a relatively benign disease of unknown etiology, marked clinical variability, and, in the military, of special significance because of the large number of man-hours lost in every case. Despite the multitude of agents used at one time or another in its treatment (1) none have been practical, and only the adrenal cortical steroids and ACTH have been found to be effective. It is generally accepted that these 2 agents should be reserved for the rare seriously ill patient (1-6).In 1958 Cronk and Naumann reported the simultaneous clinical remission of both vivax malaria and infectious mononucleosis in...References1. CRONKNAUMANN GADF: Treatment of infectious mononucleosis; a review of 1500 cases. Postgrad. Med. 23: 605, 1958. CrossrefMedlineGoogle Scholar2. MORTONHARRY CEWM: Severe infectious mononucleosis treated with prednisolone. Ann. Intern. Med. 50: 218, 1959. LinkGoogle Scholar3. MANDELMARILLEYGAINES WRJLM: Corticotropin in severe anginose infectious mononucleosis. JAMA 158: 1071, 1955. Google Scholar4. DORANWEISBURGER JUAA: The use of ACTH in infectious mononucleosis. Ann. Intern. Med. 38: 1058, 1953. LinkGoogle Scholar5. WINTROBE MM: Clinical Hematology, 5th Ed., Lea & Febiger, Philadelphia, 1961, p. 1106. Google Scholar6. CECILLOEB RLRF: A Textbook of Medicine, 10th Ed., W. B. Saunders Company, Philadelphia & London, 1959, p. 83. Google Scholar7. GOTHBERG LA: Severe infectious mononucleosis treated with chloroquine phosphate. JAMA 173: 53, 1960. CrossrefMedlineGoogle Scholar8. GOTHBERG LA: Chloroquine in the treatment of infectious mononucleosis. Schoch Letter, August 1960, p. 1. Google Scholar9. CASTLE WB: Editorial comment, in Year Book of Medicine, Year Book Medical Publishers, Inc., Chicago, 1961-1962, p. 722. Google Scholar10. PAULBUNNELL JRWW: The presence of heterophile antibodies in infectious mononucleosis. Amer. J. Med. Sci. 183: 90, 1932. CrossrefGoogle Scholar11. DAVIDSOHN I: Serological diagnosis of infectious mononucleosis. JAMA 108: 289, 1937. CrossrefGoogle Scholar12. HOAGLANDMCCLUSKEY RJRT: Hepatitis in mononucleosis. Ann. Intern. Med. 43: 1019, 1955. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: RAY G. COWLEY; JOHN E. MYERSJR.Affiliations: From the Medical Service, DeWitt Army Hospital, Fort Belvoir, Virginia.Requests for reprints should be addressed to Lieutenant Colonel Ray G. Cowley, MC, P.O. Box 325, Fitzsimons General Hospital, Denver 30, Colorado. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySafety of Short-Term Treatments with Oral Chloroquine and Hydroxychloroquine in Patients with and without COVID-19: A Systematic ReviewEffects of chloroquine or hydroxychloroquine treatment on non‐SARS‐CoV2 viral infections: A systematic review of clinical studiesEffect of chloroquine on cellular immune responses of normal and P. knowlesi -infected rhesus monkeysTreatment of Infectious Mononucleosis with Metronidazole in the Pediatric Age GroupMononucleosis infectiosa (Pfeiffer'sches Drüsenfieber)Mononucleosis infectiosa (Pfeiffer'sches Drüsenfieber)Lysosomes and TransformationSuppression of in Vitro Lymphocyte Responses by Chloroquine 1 December 1962Volume 57, Issue 6Page: 937-945KeywordsAdrenocorticotropic hormoneArmed forcesChloroquineEtiologyInfectious diseasesMalariaMedical servicesPharyngitisSteroids ePublished: 1 December 2008 Issue Published: 1 December 1962 PDF downloadLoading ...