Introduction Health information technology (HIT) is often promoted as a way to improve care and reduce cost, yet prior evidence shows uneven returns. We argue that HIT creates the greatest value when applied to chronic diseases with three characteristics: high (A)voidable costs, actionable (B)iomarker data, and established (C)linical understanding.Objectives We develop and test this A-B-C framework using longitudinal patient-level data from the Vermont Blueprint for Health (VBH), a U.S. state initiative that integrated payer, provider, and clinical data through shared HIT infrastructure.Methodology We compare outcomes for patients treated in VBH clinics and non-VBH clinics across eight chronic diseases. We classify these diseases into three tiers based on the presence or absence of the A-B-C characteristics, and estimate annual cost differences associated with VBH participation.Results HIT-associated savings are smallest for diseases lacking the full A-B-C profile, larger for diseases with strong clinical understanding alone, and greatest for the three diseases that exhibit all three A-B-CCharacteristics diabetes, breast cancer, and chronic obstructive pulmonary disease.Practical Implication HIT value depends on disease context rather than technology alone. The A-B-C framework identifies where interconnected HIT infrastructure is most likely to translate into improved care and lower costs.
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Thompson et al. (2026) studied this question.
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