Key result
Primary thoracic soft tissue sarcomas show ~64% five-year survival, worsened by grade 3 disease.
Why the study?
Primary thoracic soft tissue sarcomas are rare and limited published information is available regarding their prognostic factors and clinical outcomes.
Population
109 patients with primary thoracic soft tissue sarcomas treated between 2003 and 2013
Design
Retrospective multicenter cohort study
Follow-up
Median 29 months (range: 1-121 months)
Authors
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May inform prognosis counseling by grade and site; leaves open prospective validation before guiding therapy.
Cohort (n=109)
Yes
In patients with primary thoracic soft tissue sarcomas, low-grade tumors and chest wall localization are associated with better survival outcomes.
Ünal et al. (2014) conducted a cohort in Primary thoracic soft tissue sarcoma (n=109). Grade 3 disease and tumor location other than chest wall vs. Low-grade tumors and chest wall localization was evaluated on Survival. Primary thoracic soft tissue sarcomas had a median survival of 40.3 months (5-year survival 63.5%), with grade 3 disease and non-chest wall location confirmed as poor prognostic factors.
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