OBJECTIVES: Ga generator in Iran and evaluate the absorbed doses in numerous organs with high accuracy. METHODS: The optimized conditions for preparing the radiolabeled complex were determined via several experiments by changing the ligand concentration, pH, temperature and incubation time. Radiochemical purity of the complex was assessed, using high-performance liquid chromatography and instant thin-layer chromatography. The absorbed dose of human organs was evaluated, based on biodistribution studies on Syrian rats via Radiation Absorbed Dose Assessment Resource Method. RESULTS: Ga-DOTATOC. CONCLUSION: Ga-DOTATOC can be considered as an effective agent for clinical PET imaging in Iran.
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Naderi et al. (2016) studied this question.
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