Key result
Explosive resistance training fails to alter MyHC or titin isoform expression versus controls.
Why the study?
The effects of different loads during explosive jump squat training on myosin heavy chain and titin isoform expression in trained subjects were unclear.
Does explosive resistance training alter myosin heavy chain and titin isoforms in male athletic subjects?
Does explosive resistance training alter myosin heavy chain and titin isoforms in male athletic subjects?
An 8-week period of explosive resistance training results in negligible changes in the expression of MyHC or titin isoforms in trained male athletes.
Negligible MyHC/titin isoform changes after 8-week explosive training in athletes; leaves open longer protocols or other populations.
The purpose of this investigation was to evaluate changes in myosin heavy chain (MyHC) and titin isoforms after using various loads during explosive jump squat training. Twenty-four male athletic subjects were recruited for this study. Two experimental groups performed 8-weeks of jump squats using either 30% (n = 9) or 80% (n = 9) of their previously determined 1 repetition maximum. A third group served as controls (n = 6). Muscle biopsies were obtained before and after 8 weeks from vastus lateralis. The analysis of titin within these subjects confirmed that human skeletal muscle contains 2 isoforms of titin. There was no significant group x time interaction for MyHC or titin isoform expression. The data from this investigation indicates that a relatively short period of explosive resistance training results in negligible changes in the expression of MyHC or titin isoforms.
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McGuigan et al. (2003) studied Healthy athletic subjects (n=24). Explosive jump squat training vs. Control group was evaluated on Changes in myosin heavy chain (MyHC) and titin isoforms expression. Explosive resistance training for 8 weeks using 30% or 80% of 1RM resulted in negligible changes in the expression of MyHC or titin isoforms compared to controls.
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