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A highly efficient and improved synthetic methodology for the preparation of 3,4-dihydropyrimidin-2(1 H )-one derivatives in good to excellent yield via Biginelli reaction of β-ketoesters/β-diketone, urea/thiourea and various aldehydes using new, efficient and recyclable sulfated polyborate catalyst under the solvent-free condition is reported.
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Khatri et al. (2016) studied this question.
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