Controlled feeding trial demonstrates dose-dependent growth inhibition and organ toxicity in steers fed high aflatoxin concentrations, highlighting safe dietary exposure thresholds.
ConclusionsUnder simulated practical conditions, graded levels of aflatoxin fortified cottonseed meal were fed to young beef cattle. The levels of aflatoxin B1 fed in the ration to groups of 10 steers for 133-196 days were 0, 100, 300, 700, and 1000 parts per billion (ppb). Significant growth inhibition, decreased feed efficiencies, and increased liver and kidney weights were observed in the steers fed 700 and 1000 ppb. Gross evidence of liver damage in these groups was also detected. No apparent abnormalities were seen in the groups fed 100 and 300 ppb aflatoxin.
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Garrett et al. (1968) studied this question.
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