Studies on Pyrimidine-Annulated Heterocycles: A Short Synthesis of Novel 6,9-Disubstituted Cyclohepta[b]pyrimido[5,4-d]pyrrole-8(6H),10(9H)-diones

All articles of this category A number of 6,9-disubstituted cyclohepta[ b ]pyrimido[5,4- d ]pyrrole-8(6 H ),10(9 H )-dione derivatives have been synthesized in good to moderate yields by the reaction of 6-amino-3-methyluracil derivatives with 2-chlorotropone in an enamine-alkylation process, subsequent condensation of the amino group with the carbonyl function, dehydrochlorination, and dehydration. cyclohepta[ b ]pyrimido[5,4- d ]pyrrole - 1-azaazulene - 2-chlorotropone - 6-amino-3-methyluracil - enamine-alkylation