This commentary highlights a retrospective cohort study assessing the frequency and determinants of late adverse maternal cardiac events after pregnancy in women with congenital heart disease.
Commentary on: 1. Balint OH, 2. Siu SC, 3. Mason J, 4. et al . Cardiac outcomes after pregnancy in women with congenital heart disease. Heart 2010;96:1656–61. [OpenUrl][1][Abstract/FREE Full Text][2] Most women with congenital heart disease can now expect to reach childbearing age. Collectively, congenital malformations are the most common form of heart disease in pregnant women and the leading cardiac cause of maternal morbidity and mortality.1 Over the past two decades, several studies have characterised pregnancy-related changes, assessed maternal and fetal complications and identified related high-risk features. However, risk-stratification attempts have largely focused on acute pregnancy-related complications. Little is known about cardiac outcomes beyond the immediate peripartum setting. It is in this context that Balint and colleagues systematically assessed the frequency and determinants of adverse maternal cardiac events late after pregnancy in women with a broad spectrum of congenital heart malformations. A retrospective cohort study included 405 pregnancies in 318 women with congenital heart disease, hypertrophic cardiomyopathy or Marfan syndrome, followed at a tertiary centre in Toronto between … [1]: {openurl}?query=rft.jtitle%253DHeart%26rft.stitle%253DHeart%26rft.issn%253D0007-0769%26rft.aulast%253DBalint%26rft.auinit1%253DO.%2BH.%26rft.volume%253D96%26rft.issue%253D20%26rft.spage%253D1656%26rft.epage%253D1661%26rft.atitle%253DCardiac%2Boutcomes%2Bafter%2Bpregnancy%2Bin%2Bwomen%2Bwith%2Bcongenital%2Bheart%2Bdisease%26rft_id%253Dinfo%253Adoi%252F10.1136%252Fhrt.2010.202838%26rft_id%253Dinfo%253Apmid%252F20937754%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=heartjnl&resid=96/20/1656&atom=%2Febmed%2F16%2F3%2F93.atom
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Khairy et al. (2011) conducted an editorial in Congenital heart disease, hypertrophic cardiomyopathy or Marfan syndrome (n=318). Pregnancy was evaluated on Adverse maternal cardiac events late after pregnancy.
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