Key result
Common AV valve repair during bidirectional Glenn improves Fontan completion and prognosis in heterotaxy syndrome.
Why the study?
Common atrioventricular valve regurgitation in functional single ventricle with heterotaxy syndrome remains a challenge to overcome for Fontan completion and long-term survival.
While surgical techniques for common atrioventricular valve repair in heterotaxy syndrome have improved, early intervention before the Glenn procedure still carries a poor prognosis, highlighting the need for better techniques and small-diameter artificial valves.
May inform staged repair decisions in heterotaxy single ventricle; leaves open need for prospective validation before practice change.
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Hoashi et al. (2021) conducted a review in Functional single ventricle associated with heterotaxy syndrome and common atrioventricular valve regurgitation. Common atrioventricular valve repair was evaluated. Common atrioventricular valve repair is preferred at the timing of bidirectional Glenn to achieve Fontan operation and improve prognosis in patients with functional single ventricle and heterotaxy syndrome.
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