Key result
Cryoablation of pediatric right septal accessory pathways yields ~88% acute success without permanent AV block.
Why the study?
Radiofrequency catheter ablation near the atrioventricular node or His bundle carries increased risk of irreversible complications, prompting evaluation of cryoablation safety and efficacy in pediatric right anteroseptal or midseptal accessory pathways.
Does cryoablation safely and effectively treat right anteroseptal or midseptal accessory pathways in pediatric patients with PSVT?
Observational (n=26)
No
Does cryoablation safely and effectively treat right anteroseptal or midseptal accessory pathways in pediatric patients with PSVT?
Cryoablation is a safe and effective treatment for right anteroseptal or midseptal accessory pathways in pediatric patients, with high acute success and no permanent high-degree AV block.
May support cryoablation for right septal APs in children; hypothesis-generating and requires prospective validation.
BACKGROUND: Radiofrequency catheter ablation (RFCA) in the septum close to the atrioventricular node or His bundle has an increased risk of irreversible complications. Cryothermal energy has the advantages of reversible cryomapping and increased catheter stability. The study aims to evaluate the efficacy and safety of cryoablation of the right anteroseptal or midseptal accessory pathways (APs) in pediatric patients. METHOD: A retrospective review was performed with 26 pediatric patients (16 males and 10 females; median age 6.0 years and average body weight 24.9 kg) with paroxysmal supraventricular tachycardia (PSVT) in our Pediatric Heart Center from 2014 to 2016. Half of them had manifest APs. All the children underwent cryoablation for the treatment of PSVT because of the right anteroseptal or midseptal APs (16 cases had right anteroseptal APs and 10 cases had right midseptal APs). RESULTS: Acute cryoablation success was achieved in 23 cases (88%, 23/26). Atrioventricular block (AVB) occurred in eight cases (31%, 8/26) during the procedures and normal atrioventricular conduction recovered in seven cases except a case with I°AVB. During follow-up, three cases recurred (13%, 3/23) and no permanent high degree AVB was found. CONCLUSION: Cryoablation of the right anteroseptal or midseptal APs in pediatric patients is both safe and effective.
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Jiang et al. (2018) conducted an observational in Paroxysmal supraventricular tachycardia (PSVT) (n=26). Cryoablation was evaluated on Acute cryoablation success. Cryoablation of right anteroseptal or midseptal accessory pathways in pediatric patients achieved an 88% acute success rate, with no permanent high-degree atrioventricular block.
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