Key result
Senile asthenia syndrome linked to ~335% more postoperative complications and higher mortality after emergency abdominal surgery.
Why the study?
The influence of senile asthenia syndrome on treatment outcomes in older patients undergoing emergency abdominal surgery was not well evaluated.
Does senile asthenia syndrome increase postoperative complications and mortality in older patients undergoing urgent abdominal surgery?
Observational (n=161)
No
Does senile asthenia syndrome increase postoperative complications and mortality in older patients undergoing urgent abdominal surgery?
Senile asthenia syndrome is highly prevalent (50.3%) in older patients undergoing emergency abdominal surgery and is associated with increased postoperative complications and mortality.
Answers are grounded in this paper and cite their sources.
May inform perioperative risk stratification in elderly emergency surgery; leaves open whether frailty interventions alter outcomes.
Modern demographic data indicate a constant increase in the quantity older people in the general population structure. With age, the body is affected by many factors that lead to senile asthenia syndrome. The study is devoted to the evaluation of the influence of senile asthenia syndrome on older patients' treatment in emergency abdominal surgery for improvement. Materials and methods of the study. Examination and evaluation of the treatment results of 161 (100.0%) patients was based on the Municipal non-commercial enterprise "City Hospital of Emergency and Rapid Medical Care". In the first part of the group, 81 (50.3%) patients were diagnosed with cholelithiasis (CHD) and acute cholecystitis. The second part of the group of 80 (49.7%) patients was diagnosed with perforation of a stomach or duodenal ulcer. All patients were examined and operated urgently. Senile asthenia syndrome was assessed using the Edmonton Freil scale [11]. Markers of senile asthenia were: total protein, albumin, somatotropic hormone and interleukin 6. Results: It was established that hypoproteinemia with a total protein level indicators of 61.35 (55.00; 70.00) g/l, p = 0.0009, U = 1224.0 and dysproteinemia was determined in the main study group. The albumin level in the main group is also significantly reduced - 29.75 (24.70; 35.70) g/l, p = 0.0072, U = 2268.0. The level of somatotropic hormone was considerably lower in the main group 0.89 (0.12, 1.28) mlU/l compared to the comparison group 2.40 (0.33, 3.96) mlU/l, p = 0.0030, U = 2248.5. This indicated the presence of sarcopenia syndrome. The interleukin 6 level in both study groups exceeded the norm. A significant increase in the frequency and mortality of postoperative complications was determined in the group of asthenia patients. Conclusions. The frequency of senile asthenia syndrome was 50.3% among patients in emergency abdominal surgery. The Edmonton Freil scale can be a quick and effective method of diagnosing senile asthenia syndrome in emergency abdominal surgery.
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Danyliuk et al. (2024) conducted an observational in Urgent abdominal surgery (acute calculous cholecystitis and perforation of a gastric or duodenal ulcer) (n=161). Senile asthenia syndrome vs. Patients without senile asthenia syndrome was evaluated on Postoperative complications (p=0.0012). Senile asthenia syndrome significantly increased the frequency of postoperative complications (38.3% vs 8.8%, p=0.0012) and mortality (22.2% vs 3.8%, p=0.0432) in older patients undergoing emergency abdominal surgery.
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