The reaction of 2‐methylindole with pyruvic acid was studied. Two products are found to be depending on experimental conditions, including the 2:2 condensation adduct and the 2:1 condensation adduct. The reaction mechanism evidently involves a 1:1 adduct of 2‐hydroxy‐2‐(2‐methylindol‐3‐yl)‐propionic acid as an intermediate.
No takes yet. Share an insight, caveat, or question.
Zee et al. (1973) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: