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Tuberculosis due to Mycobacterium tuberculosis remains a major cause of illness and death worldwide. 1 Although progress has been made in the detection and treatment of drug-sensitive and drug-resistant M. tuberculosis , control requires an effective tuberculosis vaccine. 2 M. tuberculosis infects more than 50 million people worldwide, and those with recent infections are at higher risk for tuberculosis disease. 3 Infection in an asymptomatic person with a normal chest radiograph is diagnosed by measuring T-cell responses to M. tuberculosis antigens. The tuberculin skin test, the results of which can be confounded by previous bacille Calmette–Guérin (BCG) vaccination against M. bovis , has been replaced . . .
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Carpenter et al. (2025) studied this question.
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