Release of Glutamate and Other Amino Acids From Arthropod Nerve–muscle Preparations

Abstract —A study has been made of the release of glutamate and other amino acids from perfused leg preparations from Carcinus and Schistocerca, at rest and during stimulation of motor nerves to the leg muscles. Stimulation caused an increase in release af many amino acids. No evidence was obtained to link glutamate release from such preparations with synaptic function. If release of transmitter glutamate is to be demonstrated in arthropods, techniques must be devised to avoid contamination with large quantities of non‐transmitter glutamate.