Key result
Extracorporeal circulation enables open surgical repair in patients with severe aortic valve disease.
Why the study?
Further progress in aortic valve surgery required prolonged exposure of the aortic valve for proper evaluation and definitive correction, which was limited by previous techniques.
Observational (n=12)
An early historical case series describing the use of extracorporeal circulation and direct coronary perfusion to facilitate aortic valve surgery.
Opens surgical options for aortic valve disease; leaves open safety, efficacy, and reproducibility in larger cohorts.
It has been apparent during the developmental phase of aortic valve surgery that further progress would come only when the aortic valve could be exposed for a sufficiently long period of time to allow for the proper evaluation of the pathological features and their definitive correction. In the past, partial correction with a high operative mortality has been obtained with the use of closed techniques or hurried procedures with the patient under hypothermia. With the advent of extracorporeal circulation with the use of a mechanical pump oxygenator, 12 patients with aortic stenosis and regurgitation have been operated on during the past three years. If the patient was fortunate enough to have primarily fibrous aortic stenosis which could be corrected within a relatively short period of time, such operations could be successfully performed with use of elective cardiac arrest with potassium or acetylcholine and retrograde coronary sinus perfusion. However, if the
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Earle B. Kay (1958) conducted an observational in aortic stenosis and regurgitation (n=12). extracorporeal circulation with a mechanical pump oxygenator was evaluated. Extracorporeal circulation with a mechanical pump oxygenator was used to operate on 12 patients with aortic stenosis and regurgitation.
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