The list of phenomena which have been observed following the administration of arsphenamin and neo-arsphenamin is a lengthy one. I shall not attempt to add anything new to this subject, but I wish to emphasize a syndrome the rarity of which is attested to by a review of the literature as well as in personal communications from a number of syphilographers. To attempt to deal adequately with both polyneuritis and exfoliative dermatitis would be, I believe, too great a task for a paper of this character. For the sake of brevity, because of its infrequency and also in order to give it deserved prominence, I shall therefore confine myself almost wholly to a discussion of polyneuritis. I shall refer not only to cases following the use of arsphenamin and neo-arsphenamin, but I shall mention also other instances due to arsenic, as well as to syphilis and mercury. CASES OF ARSENIC
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B. Barker Beeson (1920) studied this question.