Electrooxidation of Glucose at Nanoporous Gold Surfaces: Structure Dependent Electrocatalysis and Its Application to Amperometric Detection

Electrooxidation of glucose is investigated at nanoporous gold (NPG) with controlled surface structures by applying different deposition charges during the formation of AgAu layers. As the deposition charge increases, the NPG surfaces exhibit smaller ligament/pore structures and the electrocatalytic oxidation of glucose becomes more effective. Voltammetric responses of NPG suggest that the electrocatalytic oxidation arises from the enrichment of (110) or (100) surface orientation of gold with higher deposition charges. The electrooxidation of glucose is retained at NPG surfaces with higher deposition charges in the presence of Cl−, which suggests possible applications to the amperometric glucose detection in biological samples.