In the present study the concentrations of IgE and histamine were determined in gingival tissue of patients with asthma (N = 15), patients with periodontitis (N = 21) and healthy controls (N = 18). Gingival IgE concentrations in the asthma group were markedly elevated confirming the results obtained in previous studies on salivary IgE concentrations. An increase of IgE was also observed in the periodontitis group. Histamine concentrations in the asthma group did not differ from the healthy controls, while in the periodontitis group a significant decrease in gingival histamine concentrations was found.
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T Hyyppä (1984) studied this question.
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