Key result
Temporary biventricular pacing post-CABG is feasible and safe with ~24% lead failure by day four.
Why the study?
The feasibility and safety of temporary biventricular pacing for 96 hours postoperatively in patients with severely reduced LV function after CABG were not established.
Is temporary biventricular pacing feasible and safe in patients with reduced left ventricular function after coronary artery bypass grafting?
Observational (n=51)
Is temporary biventricular pacing feasible and safe in patients with reduced left ventricular function after coronary artery bypass grafting?
Temporary biventricular pacing using a standard external pacing system is feasible and safe for up to 96 hours after CABG in patients with reduced left ventricular function.
Supports further evaluation of temporary BiV pacing post-CABG; leaves open clinical benefit in severe LV dysfunction.
BACKGROUND AND METHODS: Biventricular pacing improves hemodynamics after weaning from cardiopulmonary bypass in patients with severely reduced left ventricular (LV) function undergoing coronary artery bypass grafting (CABG). We examined the feasibility of temporary biventricular pacing for 96 hours postoperatively. Unipolar epicardial wires were placed on the roof of the right atrium (RA), the right ventricular (RV) outflow tract, and the LV free lateral wall and connected to an external pacing device in 51 patients (mean LV ejection fraction 35 +/- 4%). Pacing and sensing thresholds, lead survival and incidence of pacemaker dysfunction were determined. RESULTS: Atrial and RV pacing thresholds increased significantly by the 4th postoperative day, from 1.6 +/- 0.2 to 2.5 +/- 0.3 V at 0.5 ms (P = 0.03) at the RA, 1.4 +/- 0.3 V to 2.7 +/- 0.4 mV (P = 0.01) at the RV, and 1.9 +/- 0.6 V to 2.9 +/- 0.7 mV (P = 0.3) at the LV, while sensing thresholds decreased from 2.0 +/- 0.2 to 1.7 +/- 0.2 mV (P = 0.18) at the RA, 7.2 +/- 0.8 to 5.1 +/- 0.7 mV (P = 0.05) at the RV, and 9.4 +/- 1.3 to 5.5 +/- 1.1 mV (P = 0.02) at the LV. The cumulative overall incidence of lead failure was 24% by the 4th postoperative day, and was similar at the RV and LV. We observed no ventricular proarrhythmia due to pacing or temporary pacemaker malfunction. CONCLUSIONS: Biventricular pacing after CABG using a standard external pacing system was feasible and safe.
No takes yet. Share an insight, caveat, or question.
Eberhardt et al. (2007) conducted an observational in Severely reduced left ventricular function undergoing coronary artery bypass grafting (n=51). Temporary biventricular pacing was evaluated on Pacing and sensing thresholds, lead survival and incidence of pacemaker dysfunction. Temporary biventricular pacing after CABG was feasible and safe, with a 24% cumulative incidence of lead failure by the 4th postoperative day and no ventricular proarrhythmia.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: