Key result
BITA shows no difference from SITA in early postoperative global longitudinal strain.
Why the study?
Graft choices other than LAD-ITA anastomosis in CABG remain controversial and more sensitive methods are needed to detect early myocardial dysfunction.
Does bilateral internal thoracic artery (BITA) grafting compared to single ITA grafting affect early postoperative myocardial function in patients undergoing isolated CABG?
Observational (n=35)
No
Does bilateral internal thoracic artery (BITA) grafting compared to single ITA grafting affect early postoperative myocardial function in patients undergoing isolated CABG?
Early postoperative subclinical myocardial dysfunction occurs after CABG, but graft selection (single ITA vs BITA) does not significantly affect the degree of this early dysfunction.
No significant early LV strain difference by ITA vs BITA; leaves open whether longer clamp times drive subclinical changes in larger cohorts.
BACKGROUND: Graft choices other than left anterior descending artery (LAD)-internal thoracic artery (ITA) anastomosis in coronary artery bypass grafting (CABG) surgery are still controversial. Although 2-dimensional transthoracic echocardiography (2D TTE) is still the most commonly used method, more is needed to diagnose myocardial dysfunction. Ventricular strain values obtained by speckle tracking echocardiography (STE) or tissue Doppler imaging (TDI) methods can much better detect subclinical changes. This study aims to detect early postoperative myocardial function changes compared to single ITA/Bilateral Internal Thoracic Artery (BITA) use by measuring 3-dimensional ejection fraction (3D EF) and ventricular strain values and comparing them according to graft preference. METHODS: The study included 35 isolated CABG patients. All patients underwent on-pump CABG via sternotomy. The patients were divided into two groups using single ITA and BITA. Preoperative and postoperative 1st-week 3D EF and ventricular strain values of the patients were calculated using semi-automatic software. The recorded data were compared and evaluated between the two groups. RESULTS: Of The 35 patients participating in the study, 74.3% (n = 26) were male, 25.7% (n = 9) were female, and their average age was 62.7 ± 7.9 years. Preoperative 3D EF values of the patients were 54.4 ± 8.3% and postoperative 49.5 ± 8.2%. The mean preoperative Apical Long Axis Longitudinal Strain (APLAX LS) was calculated as - 16.2 ± 5.0%, 4 Chambers Longitudinal Strain (4CH LS)-16.8 ± 4.6%, 2 Chambers Longitudinal Strain (2CH LS) - 17.0 ± 4.9%, and Global Longitudinal Ventricular Strain (GLVS) - 16.7 ± 4.2%. Postoperative strain values were measured as - 15.1 ± 4.8%, - 14.7 ± 4.9%, - 14.6 ± 5.6% and - 14.8 ± 4.6%, respectively. When the groups were evaluated within themselves, the mean preoperative 3D EF of the patients in the single ITA group was 52.5 ± 8.8%, while the postoperative mean was 47.7 ± 6.0%. In the BITA group, preoperative 3D EF was 56.3 ± 7.5 and postoperative 51.4 ± 9.8. A decrease in strain values was detected in all groups except APLAX planes. CONCLUSIONS: In our study, no statistically significant difference was observed in terms of myocardial function changes according to the use of ITA/BITA. However, the decline in postoperative strain values of patients in the BITA group was more remarkable, and it was thought that this may be due to prolonged aortic cross clamp (CC) and cardiopulmonary bypass (CPB) times.
No takes yet. Share an insight, caveat, or question.
Ertürk et al. (2024) conducted an observational in Coronary artery disease requiring isolated CABG (n=35). Bilateral Internal Thoracic Artery (BITA) grafting vs. Single Internal Thoracic Artery (ITA) grafting was evaluated on Postoperative Global Longitudinal Ventricular Strain (GLVS) (p=0.931). Bilateral internal thoracic artery grafting did not significantly differ from single internal thoracic artery grafting in early postoperative global longitudinal strain (-14.9% vs -14.7%, p=0.931).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: