Entropy-derived Lewis acid–base thermodynamic parameters of solid surfaces: A generalized five-parameter framework for polar adsorption entropy and molecular organization by inverse gas chromatography

, which quantitatively relates adsorption entropy to molecular organization at solid interfaces. Strong quadratic relationships were established between adsorption entropy, entropy-derived Lewis acid-base parameters, and specific surface area, revealing highly regular structural trends across zeolites and oxides. The proposed framework establishes adsorption entropy as a powerful tool for surface characterization and provides the foundations of an Entropic Lewis Acid-Base Surface Chemistry applicable to adsorption, inverse gas chromatography, catalysis, porous materials, and interfacial phenomena.