Key result
QIDS-SR16 correlates only 0.44 with CDSS, indicating poor validity for assessing depression in psychotic disorders.
Why the study?
Self-report instruments for assessing depressive symptoms in patients with psychotic disorders are scarce, and the QIDS-SR16 has received little attention in this field.
Does the QIDS-SR16 reliably and validly assess depressive symptoms in patients with psychotic disorders?
Cross-Sectional (n=621)
Yes
Does the QIDS-SR16 reliably and validly assess depressive symptoms in patients with psychotic disorders?
Although the QIDS-SR16 has good internal consistency, its poor concurrent validity with the CDSS suggests it is not suitable for assessing depressive symptoms in patients with psychotic disorders.
QIDS-SR16 shows limited concurrent validity with CDSS in psychosis; leaves open need for validated self-report depression tools in this population.
BACKGROUND: Self-report instruments for the assessment of depressive symptoms in patients with psychotic disorders are scarce. The Quick Inventory of Depressive Symptoms (QIDS-SR16) may be a useful self-report instrument, but has received little attention in this field. This paper aimed to test the psychometric properties of the QIDS-SR16 questionnaire in patients with a psychotic disorder. METHODS: Patients diagnosed with a psychotic disorder from health care institutions in The Netherlands were included in the study. Depressive symptoms were assessed with the QIDS-SR16 and the Calgary Depression Scale for Schizophrenia (CDSS). Psychotic symptoms were assessed with the Positive and Negative Syndrome Scale (PANSS) and extrapyramidal symptoms (EPS) with three EPS rating scales. Spearman's correlation coefficients were used to compare the total score of the QIDS-SR16 with the total scores of the CDSS, PANSS-subscales and EPS rating scales. RESULTS: In a sample of 621 patients with psychotic disorders, the QIDS-SR16 showed good internal consistency (α = 0.87). The QIDS-SR16 correlated moderately with the CDSS (r = 0.44) and the PANSS subscale for emotional distress (r = 0.47). The QIDS-SR16 showed weak correlation with the PANSS subscale for negative symptoms (r = 0.28) and minimal correlation with EPS rating scales (r = 0.09-0.16). CONCLUSIONS: The QIDS-SR16 may reliably assess depressive symptoms in patients with psychotic disorders, but its concurrent validity with the CDSS was rather poor in this population. We would recommend developing a new self-report questionnaire for the assessment of depressive symptoms in patients with psychotic disorders.
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Lako et al. (2014) conducted a cross-sectional in Psychotic disorders (schizophrenia, schizoaffective disorder, etc.) (n=621). QIDS-SR16 questionnaire vs. Calgary Depression Scale for Schizophrenia (CDSS) was evaluated on Concurrent validity (Spearman correlation) between QIDS-SR16 and CDSS total scores (r = 0.44, 95% CI 0.38-0.51, p=<0.001). The QIDS-SR16 self-report questionnaire showed good internal consistency but correlated only moderately (r = 0.44) with the interview-based CDSS, indicating poor concurrent validity for assessing depressive symptoms in patients with psychotic disorders.
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