Development of Ti-15Zr-Mo alloys for applying as implantable biomedical devices

In this study, the effect of molybdenum content in Ti-15Zr-based alloys (wt%) was analyzed in terms of crystalline structure, microstructure, selected mechanical properties, and cytotoxicity.The samples were produced by argon arc-melting followed by hot rolling and heat treatment processes.The crystalline structure and microstructure were dependent of both alloying elements (zirconium and molybdenum).Ti-15Zr alloy displayed only laths of a 0 phase, while the alloys up to Ti-15Zr-10Mo exhibited different proportions of a 0 , a", and b phases.Molybdenum content higher than 12.5 wt% fully stabilized the b phase.Vickers microhardness values of Ti-15Zr-Mo alloys were higher than those of CP-Ti due to solid solution and phase precipitation strengthening.Young's modulus values of Ti-15Zr-Mo alloys were lower than those of CP-Ti due to b phase stabilization.Cytotoxicity levels of Ti-15Zr-Mo alloys were within a tolerable range for biomedical purposes.In addition, we observed molybdenum content in Ti-15Zr-based alloys promoted an increase on pre-osteoblast adhesion up to 3 h of adhesion's time.Thus, Ti-15Zr-15Mo alloy presented better combination of properties than some traditional metallic biomaterials.