Neurotoxic Reaction to Chloromycetin

Case Reports1 June 1952NEUROTOXIC REACTION TO CHLOROMYCETINLEONARD WALLENSTEIN, M.D., JEROME SNYDER, M.D.LEONARD WALLENSTEIN, M.D.Search for more papers by this author, JEROME SNYDER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-36-6-1526 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn the few years since the isolation and synthesis of Chloromycetin, a profusion of reports has attested its value and wide chemotherapeutic range. It has also been attractive because of its non-toxic character and because it is equally satisfactory by oral and parenteral route.Toxicity studies in animals and man have shown Chloromycetin to be practically free of both acute and chronic toxicity at levels well within the therapeutic range, even after administration over a long period. A single report1of three cases (two typhoid and one acute brucellosis) treated with the drug records a significant fall in the number...Bibliography1. Volini IF: Hemopoietic changes during administration of Chloramphenicol, J. A. M. A. 142: 1333, 1950. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Baltimore, Maryland*Received for publication November 19, 1951. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byScientific Opinion on Chloramphenicol in food and feedIatrogenic neurologyCHLORAMPHENICOLSystematic Reviews of Animal Experiments Demonstrate Poor Human Clinical and Toxicological UtilityClindamycin, Metronidazole, and ChloramphenicolThe Neurotoxicity of Antibacterial AgentsSHARON R. SNAVELY, M.D., GLENN R. HODGES, M.D.Chloramphenicol-Induced Acute Bilateral Optic Neuritis in Cystic FibrosisNeurotoxicity with Chloramphenicol—An Electron Microscopic StudyDrug Induced Retinopathy�ber die Furacin-Retinopathie beim KaninchenRetinopathy Due to ChloramphenicolSeptic arthritis due toPseudomonas pseudomalleiParalysis, Incoordination and Involuntary MovementsAdrenal cortical carcinomaOptic neuritis with prolonged use of chloramphenicolVisual disturbances in cystic fibrosis following chloramphenicol administrationThe Effects of Drugs upon the EyeOPTIC ATROPHY INDUCED BY CHLORAMPHENICOLRetinopathy of Obscure (Toxic?) Origin in Hodgkin's Disease*Clinical and therapeutic observations in adrenal cancer: A report on 7 patients treated with o,p'-dddToxic Amblyopia Due to ChloramphenicolBLINDNESS DURING STREPTOMYCIN AND CHLORAMPHENICOL THERAPYChronic systemic melioidosisA Toxic Ocular Manifestation of Chloramphenicol TherapyAntibiotikaUntoward Reactions to Antibiotics 1 June 1952Volume 36, Issue 6Page: 1526-1528KeywordsBrucellosisDrugsFallsToxicityTyphoid Issue Published: 1 June 1952 PDF downloadLoading ...