Development of multidrug resistance during treatment of isoniazid-resistant tuberculosisTo the Editors: Several treatment regimens have been recommended for the treatment of isoniazid-resistant tuberculosis (TB).However, an optimal regimen and duration for this treatment remains a matter of some controversy.Here, we would like to share our experience in a case of pulmonary TB with acquired multidrug resistance, during a 12-month treatment of isoniazid-resistant TB with rifampin and ethambutol, with pyrazinamide administered during the initial 2 months.
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Koh et al. (2005) studied this question.
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