Key result
New 3D antroduodenal model evaluates node dislocation during peristalsis to assess peroral chemical exposure risks.
Why the study?
A sub-model of the digestive system at the meso-level is being developed to assess functional disorders caused by environmental factors, focusing on the antroduodenal area.
The developed 3D model of antroduodenal motility can be applied in health risk assessment for peroral exposure to chemicals.
May aid peroral chemical risk assessment; leaves open empirical validation before any practice integration.
As a part of multi-level model of accumulation of functional disorders in the human body under the influence of environmental factors, the sub-model of "meso-level" of digestive system is being developed.The article highlights the tasks of reconstruction of 3D model of antroduodenal area of the gastrointestinal tract and evaluation of nodes dislocation of the computational grid at the passing of peristaltic wave in gastric antrum and pyloric sphincter motor activity.The observed approaches could be applied in health risk assessment at peroral exposure to chemicals.
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Marat R. Kamaltdinov (2014) studied Health risks from peroral exposure to chemicals. 3D modeling of antroduodenal zone motility was evaluated on Reconstruction of 3D model of antroduodenal area and evaluation of nodes dislocation. A 3D model of the antroduodenal area was developed to evaluate nodes dislocation during peristaltic waves for assessing health risks from peroral chemical exposure.
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