Quality control to manage unsealed radioactive sources in nuclear medicine

This is the authors' abstract. We don't add key points for this paper.

According to the domestic and international regulatory framework of radiological protection, medical exposures of patients were regarded generally justified.However, there would be probability of discrepancy between prescribed dosage (or activity) and administered one during radiopharmaceutical delivery procedures.Due to inherent source of uncertainties, the discrepancies were reported up to ±10 to 20 % for assuming well developed and good practices.So, the accurate assay of radiopharmaceuticals prior to administration is important process to assure that patients receive the correct prescribed dosage.In nuclear medicine practices, dose calibrators (radionuclide calibrators), usually well-type ionization chambers equipped with electrical circuit, have been used as the principal instrument to assay radiopharmaceutical dosage.Domestic regulation required licensee to maintain the patients' administered activity as prescribed by medical doctors.Based on the requirement, technical standards for activity measurements of unsealed radioactive sources in nuclear medicine practices and possession of measurement instruments were developed.Survey on current states of activity measurement in nuclear medicine practices, usage and quality control of dose calibrators and internationally recognized standards for quality control of dose calibrators were conducted to design appropriate regulatory approach.