Inverse relationship between age and severity and sequelae of acute corneal hydrops associated with keratoconus

a novel phenotype in our patient in the Alstro ¨m locus.As this is a single case, we cannot be certain that the retinal exudation is definitely caused by this mutation.Our patient however had unilateral exudative retinopathy.This may be due to an asymmetry of the retinal dystrophy between the eyes.The natural history of this retinopathy is unknown and the beneficial results of treatment varying from photocoagulation, 8 cryotherapy 9 and pars plana vitrectomy 10 are difficult to quantify.It is possible that in time, the other eye may become affected, probably as the retinal dystrophic changes progress.