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A thermoresponsive crown ether/amine-type rotaxane switch worked under solvent-free condition was developed. The wheel component moved to switch the local position on the axle by the solid-state acid–base reaction between tert-amine moiety of the rotaxane and trichloroacetic acid. The wheel shuttling on the axle proceeded via neutralization by heating and protonation with trichloroacetic acid, being confirmed by 1H NMR and TGA.
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Zhu et al. (2016) studied this question.
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