Symptomatic Myopathy due to Red Yeast Rice

Letters19 September 2006Symptomatic Myopathy due to Red Yeast RicePaul S. Mueller, MDPaul S. Mueller, MDFrom the Mayo Clinic, Rochester, Minnesota.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-145-6-200609190-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: Red yeast rice is a dietary supplement that contains 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors and is used for self-treatment of hyperlipidemia.Objective: To report a case of symptomatic myopathy associated with use of red yeast rice.Case Report: In January 2005, a 61-year-old woman presented for a general health assessment. She reported a history of hyperlipidemia but had no symptoms at rest or with activities. Her medications included an estradiol transdermal patch (0.05 mg/wk), aspirin (81 mg/d), and a multivitamin (once daily). Her vital signs were normal, weight was 70.9 kg, and body mass index was 29.2 kg/m2. ...References1. Thompson Coon JS, Ernst E. Herbs for serum cholesterol reduction: a systematic view. J Fam Pract. 2003;52:468-78. [PMID: 12791229] MedlineGoogle Scholar2. Heber D, Yip I, Ashley JM, Elashoff DA, Elashoff RM, Go VL. Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement. Am J Clin Nutr. 1999;69:231-6. [PMID: 9989685] CrossrefMedlineGoogle Scholar3. Prasad GV, Wong T, Meliton G, Bhaloo S. Rhabdomyolysis due to red yeast rice (Monascus purpureus) in a renal transplant recipient. Transplantation. 2002;74:1200-1. [PMID: 12438974] CrossrefMedlineGoogle Scholar4. Smith DJ, Olive KE. Chinese red rice-induced myopathy. South Med J. 2003;96:1265-7. [PMID: 14696880] CrossrefMedlineGoogle Scholar5. Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, Van Rompay M, et al. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA. 1998;280:1569-75. [PMID: 9820257] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Paul S. Mueller, MDAffiliations: From the Mayo Clinic, Rochester, Minnesota.Acknowledgment: Editing, proofreading, and reference verification were provided by the Section of Scientific Publications, Mayo Clinic.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoSymptomatic Hepatitis Associated with the Use of Herbal Red Yeast Rice Harry Roselle , Andrew Ekatan , Jausheng Tzeng , Mark Sapienza , and Jeffrey Kocher Red Yeast Rice for Dyslipidemia in Statin-Intolerant Patients Anna L. Kolpakchi , Ikedieze I. Chukwu , and Maria T. Vlachaki Red Yeast Rice for Dyslipidemia in Statin-Intolerant Patients David G. 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Rader, MDSymptomatic Hepatitis Associated with the Use of Herbal Red Yeast RiceHarry Roselle, MD, Andrew Ekatan, MD, Jausheng Tzeng, MD, Mark Sapienza, MD, and Jeffrey Kocher, MDA case report of myopathy from consumption of red yeast riceOne-Month Therapy with Simvastatin Restores Endothelial Function in Hypercholesterolemic Children and Adolescents 19 September 2006Volume 145, Issue 6Page: 474-475KeywordsCreatine kinaseExerciseHyperlipidemiaMyalgiaResearch laboratoriesThoraxThyroidThyroid-stimulating hormoneVital signsWeight loss ePublished: 19 September 2006 Issue Published: 19 September 2006 Copyright & PermissionsCopyright © 2006 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...