Key result
The electrochemical immunomagnetic sandwich assay successfully detected IL-6 in human plasma and cellular media, decreasing the time to concentration readout to approximately one hour.
The developed electrochemical immunomagnetic assay can detect IL-6 in human plasma with a readout time of approximately one hour, showing potential for future point-of-care diagnostics.
range, which is a physiologically relevant IL-6 range for a variety of biological systems. The sandwich assay performed well in phosphate buffered solution as well as in cellular media and human plasma spiked with IL-6, and decreased time to IL-6 concentration readout to approximately one hour. There is also future potential to apply this assay to real-time point-of-care human disease diagnostics.
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Buckey et al. (2024) studied Interleukin-6 detection. Electrochemical immunomagnetic sandwich assay was evaluated on Time to IL-6 concentration readout. The electrochemical immunomagnetic sandwich assay successfully detected IL-6 in human plasma and cellular media, decreasing the time to concentration readout to approximately one hour.
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