being R for rehydration, 0 for oral fluid replacement, S for simultaneous intravenous rehydration, and E for education of mothers about diarrhoea and dehydration.This is very important and in large Indonesian cities a child's admission to hospital is often one of the few opportunities for this educational process to occur.This ROSE method is now being used on a nation-wide basis.These results represent a marked improvement over recent years.In 1963 the mortality rate from childhood cholera in Jakarta was 46 ",, when glucose-saline was given intra- venously.In 1973 the mortality rate dropped to 10",, when sodium bicarbonate was added to the intravenous fluid, in 1974 it dropped even further to 3-5",, when Ringer's lactate was given intravenously followed by glucose- electrolyte solution orally.This simple ROSE system could be used in large hospitals where facilities for intravenous therapy are available.Minor modifications, such as the substitution of sucrose for glucose, in the oral fluid should not adversely affect the results.Sucrose is much more readily available and much cheaper and has been shown to be very useful in the oral treatment of this disease.
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Alex Scott-Samuel (1977) studied this question.