Key result
Adenotonsillectomy fails to alter mean platelet volume in children with adenotonsillar hypertrophy.
Why the study?
Adenotonsillar hypertrophy causes hypoventilation leading to cardiac and pulmonary dysfunctions and potential hypercoagulopathy, but changes in mean platelet volume after adenotonsillectomy are unclear.
Does adenotonsillectomy reduce mean platelet volume in children with adenotonsillar hypertrophy?
Observational (n=45)
No
Does adenotonsillectomy reduce mean platelet volume in children with adenotonsillar hypertrophy?
Adenotonsillectomy in children with adenotonsillar hypertrophy does not significantly change mean platelet volume, though it decreases overall platelet count.
Answers are grounded in this paper and cite their sources.
Does not support adenotonsillectomy to modify mean platelet volume; observational data leave open effects on other pediatric cardiovascular markers.
Objective: Adenotonsillar hypertophy is the most common cause of upper airway obstruction seen in children.Adenotonsillar hypertrophy is known to cause cardiac and pulmonary disfunctions.The most important reason for this is hypoventilation.Hypoventilation could lead to hypercoagulopathy.Mean platelet volume is the most important parameter that shows thrombocyte size.Larger thrombocytes contain more enzymatic granules and this is an indication that more prothrombotic activities will occur.In this study we researched on the changes in Mean platelet levels after adenotonsillectomy in patients with adenotonsillar hypertrophy. Methods:The mean platelet volume of 45 patients of ages 3-9years were retrospectively evaluated before and after operation due to adenotonsillar hypertrophy between the years 2011-2015.Results: There was no significant difference in Hemoglobin, White blood cells, and Mean Platelet Volume between the preoperative and postoperative values however there was a significant decrease in platelet count. Conclusion:There was no signifant change in Mean Platelet Volume but a decrease in platelet volume was seen in almost 50% of the patients.
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Mitat Arıcıgil (2017) conducted an observational in Adenotonsillar hypertrophy (n=45). Adenotonsillectomy vs. Preoperative baseline was evaluated on Mean Platelet Volume (MPV) (p=0.069). Adenotonsillectomy did not significantly change mean platelet volume in children with adenotonsillar hypertrophy at 3 months postoperatively (5.80 vs 5.55 fl, p=0.069).
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